The immune system protects us, but in the most serious cases of coronavirus it seems to be overreacting and counterproductive, as it happens in other diseases
From the cases that go unnoticed because they do not give symptoms until death: the range of reactions caused by SARS-CoV-2 is wide and perplexing. Why does the same infection have such disparate effects? If statistics tell us anything, it is that age has a lot to do with it. In the first decades of life, there are hardly any complications, although some specific cases are difficult to explain. On the other hand, as the years of the patient’s increase, hospital admissions, cases in the ICU and deaths multiply.
Can everything be explained by the existence of previous pathologies? Hypertension, diabetes and cardiovascular diseases have been identified as risk factors, but there is a more basic question: what does the immune system do when attacked by an external enemy. In the face of an unknown virus, an innate response occurs, and, later, when our defenses already recognize the pathogen, the adaptive response arrives, which acts specifically against that threat. However, something seems to be failing in the most serious patients of this new coronavirus in this second phase: an exaggerated response that ends up causing damage to the body and does not prevent the virus from multiplying.
Be very careful with the Covid-19 if you already suffer from these diseases
The SARS-CoV-2 coronavirus causes more serious cases and deaths in people suffering from other pathologies, but the mechanisms by which it occurs are unclear
“It is striking that there is a lot of heterogeneity in the clinic of this virus, and this may be related to a wide variety of immune responses, some are more effective and neutralize the virus, and others lead to the disease, ” José Manuel told Teknautas Bautista, a molecular biologist from the Complutense University of Madrid, “but we really still know very little, each virus can behave differently even if there are common characteristics among those of the same family.”
“Viruses behave differently in each individual and challenge their immune system, ” explains virologist Raúl Ortiz de Lejarazu, former director of the National Flu Center in Valladolid. “What happens in each body has to do with individual factors that we do not know well, we know in the flu and in other diseases already studied, but not in this coronavirus,” he admits.
As an example of the heterogeneity in the response to viruses, this expert gives an example he knows well: “ In the 2009 influenza A pandemic, it was soon seen that the obese reacted worse, among this group there were many more people who fell ill with seriously because they had a different inflammatory profile than people with normal weight. ”
How the immune system reacts
At the beginning of an infection, the innate response occurs — it is called that because it is common to all people against a pathogenic microorganism, even if we have not been exposed before. This works “by a very primary system: I know you or I don’t know you, you are strange or you are not .” If we do not recognize it, a series of mechanisms are set in motion, for example, we secrete proteins called interferons and cytokines. “If this occurs normally, the result is a good physiological response that tends to heal the individual,” explains the expert.
The next step is the adaptive response. “It is a response adapted to the new pathogen as if the tailor had already taken the measurements and made the right suit against the aggression, ” he says. That is why, in almost any infection, antibodies (substances to combat it) are generated from day 12 or 13, which makes the primary and innate response more effective.
However, severe cases of coronavirus appear to be related to an exaggerated response by the immune system, which experts call a “cytokine storm.” This term was coined around 15 years ago when serious cases of avian influenza in Asia were being investigated. People who reacted badly and died had secreted many inflammatory cytokines, that is, a type of protein that generates inflammatory phenomena indiscriminately in the lung and other organs. Instead of collaborating with each other, they “ generated friendly fire damage ”.
Ortiz de Lejarazu’s research group observed that the same was true in severe cases of influenza A, according to articles they published in 2011 and 2012. That cytokine storm also happens again in severe Covid-19 cases. “ Our immune system, in the effort to eliminate the virus, damages cells and organs. The end result is that it does not control the virus, which continues to multiply, “he says.
In very different diseases, it also occurs. Bautista knows the case of cerebral malaria thoroughly. “There are many people who become infected in Africa, but only a specific population group dies, children who react aggressively with their immune response. All this is very similar to what is being described ”, he points out.
Does exposure influence gravity?
Other external factors do not influence the fact that a patient reaches this serious situation, such as having been in greater contact with the disease, as happens to health professionals, according to Ortiz de Lejarazu, who warns about the confusion that is generating the viral load concept. “It is only a parameter used in medicine as if we were talking about fever. What the viral load tells us is whether a virus is multiplying too much or too little in an organism. For example, in HIV, the viral load is used to know if the person who is infected is responding well to treatments or if, on the contrary, the amount of virus in their body increases. ”
When one acquires the infecting dose, one becomes infected. If you buy three doses, 10 or 20, you get the same infection but you will not be more serious
However, in this crisis, this concept is being misrepresented, and some are implying that the virus can accumulate through continued exposure. “The toilets do not go with a backpack carrying viruses,” he clarifies, “a person becomes infected because they acquire an infectious dose, that is, a certain amount of microorganism.” Scientists calculate what viral load is needed for contagion in mouse experiments.
“When you get the infectious dose, you become infected. If you get three infectious doses, 10 or 20, you get the same infection, and that does not have any significance on what will happen next, because in reality on the second or third day of being infected, a person produces millions of infective doses. In the body, we amplify the infective dose a lot of times and there we do talk about the viral load. The only consequence of viral load is that a person who is producing more viruses has a greater ability to transmit them, “he adds.
On the other hand, José Manuel Bautista does not rule out that prolonged exposure to the virus could have something to do with severe cases. “If only a few units of the virus infect you, they could reach a few cells and perhaps the immune response would be activated progressively so that it could contain itself better,” he says. However, “this is only a hypothesis because no experiment has been done to prove it, to see if this is the case, it would be necessary to subject mice to different viral loads and that, as they increase, there comes a time when the answer immune was not efficient. ”
The coronavirus viral load appears to peak in the first week of illness, and in mild cases, it would clear rapidly. However, seriously ill patients tend to have a high viral load and a longer period of virus shedding, according to an article published in ‘The Lancet ‘. Therefore, the viral load could be a marker to assess severity and prognosis (although this is not related to the possibility that viral load is related to prolonged exposure).
In any case, in the absence of experiments that can confirm or deny this idea, the researcher at the Complutense University considers that the reason why health professionals get sick is more likely due to other factors, such as stress decreases their immune response.
Home Depot Health Check & Associate Health Check
What is Home Depot Health Check?
It is an application for the employees of Home Depot. If you are not sure about Home Depot, then let us inform you that it is all about healthcare. In this app, various types of tests are carried out without the involvement of money. Yeah, you got it right! Through this app, anyone can get free of cost blood work.
How Does Home Depot App Work?
All you have to do to get started with the app is to make an account. Once that is done, you have to log in and start using the app. This application is meant for all types of operations and systems; including Android and iOS. By the way, as soon as you sign-up, a card will be received. That will contain your credentials like name and SSC details. You may wonder what is SSC details. Well, in case you do, here are the details. The US associated health check number is given on the card which works as a reference number.
What is the use of a Home Depot Health Check?
This application is used for workers. If you ask about the aim of this app. It is to keep an eye on the health and wellness of workers. Remember, this app is only functional and used in the US.
How to Download or Install Home Depot Health Check?
Interestingly, this app is based on the web. What does it mean? It clearly means the user is able to access this application from the browser of your smartphone. Other than smartphones, it is also accessible from devices like laptops and tablets. One thing that you have to be mindful of is to have the updated version of the search engine aka browser.
Following are the steps you have to take in order to complete the installation process without any hassle or difficulty.
Step #1: Visit the site https://healthcheck.homedepot.com/. There are many fake websites out there. Be sure of opening the link mentioned here.
Step #2: As soon as you visit the website, there will be a welcome note. With that, you will see two options to choose from. The first one is “Associate” and the second is “SSC Non-Associate”.
Step #3: In case you click “Associate”, you will be redirected to another page. On that page, there will be a note for you to read. If you continue, there will be a page that will ask for your name, location, and ID. Other than that, a password will also be asked. You can press “Forgot Password” if you are unable to recall the current password. By doing so, you will get a new password.
Note: This step will be skipped naturally if you opt for the “SCC Non-Associate” option.
Step #4: If you select the “SCC Non-Associate” pick, certain info will be required to complete the form. In the form, you will be asked to fill out sections. And yes, in the sections there will be name, contact number, company name, badge ID.
Step #5: A new questionnaire will be seen in the next step. You have to fill that up to make use of the app.
Advantages and Perks of Using THD Health Check
THD Health Check comes with a lot of perks. Do you want to know some of the main ones? If yes, we have got your back! Following are those advantages that almost everyone who uses this app talks about.
Advantage #1: Associated Health Check’s Opportunities
With the Associated Health Check of Home Depot, users are given the chance to select a plan that will work for themselves and their families. Facilities and perks are given to both, non-associated as well as the associates. However, these facilities are given in the form of dental insurance, life insurance, and other kinds of healthcare benefits.
Advantage #2: Special Reductions for Associates
Special kinds of discounts are given to those who choose the “Associates” plan. If the user is an employee, he gets auto insurance too.
Advantage #3: Off Duty Benefits
Time-off as in off-duty aids is also provided by THD health check. These perks or benefits include bereavement leave, services on a jury, and vocation training.
Advantage #4: Provides Financial Perks
Last but not least, this Home Depot health check application facilitates the user with financial perks. This may include bank incentives.
Indeed, the Home Depot Health Check application is facilitating users with some cardinal and most important features. Since this app is web-based, there is a search bar that gives instant results of products of facilitations one may need.
Frequently Asked Queries about Home Depot Heath Check
Question #1: What is Home Depot Health Check?
As mentioned in the opening paragraph of this blog post. This app is based on the web. It is a unique app for the associated as well as non-associated of the US. When it comes to fitness, health, and wellness, this app is the one that helps the most.
Question #2: How can I install or download the THD health check app?
All you have to do is to visit https://healthcheck.homedepot.com/ on any device you use. By clicking the links, filling out the form, and following the remaining procedure, you will be able to access the app.
Last Words – Home Depot Health Check App
If you live in the US and are wanting to get some health benefits, start using Home Depot Health Check now! It has helped hundreds of people in this nerve-wracking pandemics. This app provides ultimate health solutions. Mainly because the app aims to give health perks to the employees.
IMPORTANT VITAMINS AND MINERALS FOR YOUR NAIL
Vitamins and minerals are critical to our overall health. A lack of vitamins and minerals can result in many health issues in our body, iron deficiency can result in anemia. In the same way, vitamins and minerals affect our overall health, they also affect our hair and nails too.
So there is a need for us to consume these vitamins and minerals in an appropriate portion to have a healthy nails (https://besttoenailfungustreatments.com/).
However, having a deficiency in most of these vitamins is not too common, because we get at least a required portion of it in our diet.
Yes, without further ado, let’s dive into the important vitamins and minerals for your nails.
Biotin is one of the most significant vitamins for your nail health, it is also called vitamin B7.
They help in promoting cell growth and also breaking down protein. Protein is very crucial in the building up of our body and repairing our worn-out tissues.
However, taking biotin as a supplement or taking food rich in biotin can boost your nail health and make them stronger.
Iron is an essential constituent in the red blood cells, the red blood cell is an oxygen-carrying portion of the blood. oxygen
For oxygen to be adequately transferred to all parts of the body, a sufficient amount of iron will be required.
The same way blood is transferred to all parts of our body, blood also needs to get to our nails
So a change in the proportion of Iron in our body can affect the blood supply getting to our nails and at the same time affect our nail health.
Iron can be found in the foods like beef dark leaf vegetables, eggs, peanuts, and beans.
Yes, another very significant mineral in our body is magnesium which is responsible for chemical reaction in our body. It is responsible for protein production, a very important reaction for our body.
Protein is crucial in our nail growth, and vertical lines in your nails can imply a sign of magnesium deficiency.
For healthy and stronger nails, take food with rich magnesium.
Vitamin C has been known for boosting the immune system and also aiding rapid healing.
It also helps bone and blood vessels. It is responsible for collagen synthesis, which gives shape and strengthens the nails.
However, this important vitamin c can’t be manufactured by the body.
So we get it mostly by consuming food rich in vitamin C such as citrus and other vegetables.
Zinc is another important mineral responsible for rapid healing.
It is responsible for the growth and division of cells. In case you don’t know nails cell divide and grow rapidly, so as a result of it, a sufficient supply of Zinc is very vital for your nail health. Not getting enough zinc can be seen as white spots on your nails.
Wrapping up, aside from the above-mentioned vitamins and minerals, there are several other B vitamins, protein, omega 3 fatty acids, and many other minerals responsible for our nail healthy.
A White Smile That Lasts: This Is What to Eat After Teeth Whitening
The average American spends over $200 on beauty products and devices yearly, and teeth whitening is no exception.
If you’re considering whitening your teeth, you’re likely wondering what to eat after teeth whitening. A sparkling white smile requires careful meal planning even after the process is finished.
Follow these meal tips for successful whitening results.
What to Eat After Teeth Whitening
Now that we know what foods to avoid, here are some foods that are good to eat after whitening your teeth. As the name implies, these are primarily white foods that are low in acidity and do not contain pigments or chemicals that can cause stains.
- Fish, Chicken, Tofu
Light and lean protein are generally healthy and great after teeth whitening. Beware of bold seasonings and sauces that go well with protein. Stick to white sauces instead.
- Rice, bread, noodles
Most grains are safe for white diets. However, be careful with bread and pasta that contain molasses and food coloring. These are often included because they can artificially give bread or pasta a dark look and transfer to the teeth.
- White cheese and yogurt
Dairy products are also a good choice, as they contain calcium and other nutrients that are good for your teeth. Skip artificially colored cheese and sweet flavored yogurt. White cheese and plain yogurt are ideal choices to eat after professional teeth whitening.
- Fresh fruits and vegetables
Light fruits and vegetables are the staple foods to eat after teeth whitening.
Fruits (pears, bananas, apples, etc.) and vegetables (cauliflower, potatoes, mushrooms, etc.) are not only healthy but also good for your teeth!
Water is the perfect drink for hydration, mouth health, and a bright smile. Water should be the best choice to drink after teeth whitening as there is no risk of soiling your teeth or wearing down your enamel.
Foods to Avoid After Teeth Whitening
Before you dive into that gallon of ice cream, here are a few foods to avoid:
- Hard candy & mints. Avoid hard candy and mints as they can cause tooth sensitivity and gum recession.
- Acidic fruits. Citruses like oranges, lemons, and grapefruits can cause tooth sensitivity.
- Coffee & Tea. Dark-colored beverages can cause staining and discoloration.
- Alcohol. Avoid alcohol as it can dry out your mouth and cause sensitivity.
- Ice. Chewing on ice can cause gum recession, tooth fractures, and sensitivity.
It is very necessary to know what not to eat after teeth whitening to prevent teeth staining that are the causes of yellow teeth.
Foods to Eat if Your Teeth Are Sensitive After Whitening
Unfortunately, the teeth whitening process sometimes causes sensitivity and other problems. However, certain foods can help to reduce these problems.
Eating hard cheeses, for example, can help to re-mineralize the teeth and reduce sensitivity. Eating yogurt can also help to reduce sensitivity by providing a source of probiotics.
Looking for a Whiter Smile?
If you are looking for a whiter smile that will last, then you should definitely consider changing your diet by knowing what to eat after teeth whitening. It is important to avoid foods and drinks that can stain your teeth. Focus on eating foods that are white or light in color.
For more interesting content, keep browsing our site!
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